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The evolution of the human DNA replication timing program

DNA is replicated according to a defined spatiotemporal program that is linked to both gene regulation and genome stability. The evolutionary forces that have shaped replication timing programs in eukaryotic species are largely unknown. Here, we studied the molecular causes and consequences of repli...

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Detalles Bibliográficos
Autores principales: Bracci, Alexa N., Dallmann, Anissa, Ding, Qiliang, Hubisz, Melissa J., Caballero, Madison, Koren, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013799/
https://www.ncbi.nlm.nih.gov/pubmed/36848554
http://dx.doi.org/10.1073/pnas.2213896120