Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage

Trypanosomatid pathogens are transmitted by blood-feeding insects, causing devastating human infections. These parasites show important phenotypic shifts that often impact parasite pathogenicity, tissue tropism, or drug susceptibility. The evolutionary mechanisms that allow for the selection of such...

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Detalles Bibliográficos
Autores principales: Bussotti, Giovanni, Li, Blaise, Pescher, Pascale, Vojtkova, Barbora, Louradour, Isabelle, Pruzinova, Katerina, Sadlova, Jovana, Volf, Petr, Späth, Gerald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013807/
https://www.ncbi.nlm.nih.gov/pubmed/36848551
http://dx.doi.org/10.1073/pnas.2220828120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013807/
https://www.ncbi.nlm.nih.gov/pubmed/36848551
http://dx.doi.org/10.1073/pnas.2220828120

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