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Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage
Trypanosomatid pathogens are transmitted by blood-feeding insects, causing devastating human infections. These parasites show important phenotypic shifts that often impact parasite pathogenicity, tissue tropism, or drug susceptibility. The evolutionary mechanisms that allow for the selection of such...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013807/ https://www.ncbi.nlm.nih.gov/pubmed/36848551 http://dx.doi.org/10.1073/pnas.2220828120 |