Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury

Efficient in vivo delivery of anti-inflammatory proteins to modulate the microenvironment of an injured spinal cord and promote neuroprotection and functional recovery is a great challenge. Nucleoside-modified messenger RNA (mRNA) has become a promising new modality that can be utilized for the safe...

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Detalles Bibliográficos
Autores principales: Gál, László, Bellák, Tamás, Marton, Annamária, Fekécs, Zoltán, Weissman, Drew, Török, Dénes, Biju, Rachana, Vizler, Csaba, Kristóf, Rebeka, Beattie, Mitchell B., Lin, Paulo J.C., Pardi, Norbert, Nógrádi, Antal, Pajer, Krisztián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013810/
https://www.ncbi.nlm.nih.gov/pubmed/36930811
http://dx.doi.org/10.34133/research.0056

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