Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase

The enzyme soybean lipoxygenase (SLO) provides a prototype for deep tunneling mechanisms in hydrogen transfer catalysis. This work combines room temperature X-ray studies with extended hydrogen–deuterium exchange experiments to define a catalytically-linked, radiating cone of aliphatic side chains t...

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Detalles Bibliográficos
Autores principales: Zaragoza, Jan Paulo T., Offenbacher, Adam R., Hu, Shenshen, Gee, Christine L., Firestein, Zachary M., Minnetian, Natalie, Deng, Zhenyu, Fan, Flora, Iavarone, Anthony T., Klinman, Judith P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013837/
https://www.ncbi.nlm.nih.gov/pubmed/36867685
http://dx.doi.org/10.1073/pnas.2211630120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013837/
https://www.ncbi.nlm.nih.gov/pubmed/36867685
http://dx.doi.org/10.1073/pnas.2211630120

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