Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G protein

G protein-coupled receptors (GPCRs) represent the largest group of membrane receptors for transmembrane signal transduction. Ligand-induced activation of GPCRs triggers G protein activation followed by various signaling cascades. Understanding the structural and energetic determinants of ligand bind...

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Detalles Bibliográficos
Autores principales: Han, Yanxiao, Dawson, John R. D., DeMarco, Kevin R., Rouen, Kyle C., Bekker, Slava, Yarov-Yarovoy, Vladimir, Clancy, Colleen E., Xiang, Yang K., Vorobyov, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013855/
https://www.ncbi.nlm.nih.gov/pubmed/36853938
http://dx.doi.org/10.1073/pnas.2215916120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013855/
https://www.ncbi.nlm.nih.gov/pubmed/36853938
http://dx.doi.org/10.1073/pnas.2215916120

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