Mouse models of human multiple myeloma subgroups

Multiple myeloma (MM), a tumor of germinal center (GC)-experienced plasma cells, comprises distinct genetic subgroups, such as the t(11;14)/CCND1 and the t(4;14)/MMSET subtype. We have generated genetically defined, subgroup-specific MM models by the GC B cell-specific coactivation of mouse Ccnd1 or...

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Detalles Bibliográficos
Autores principales: Winkler, Wiebke, Farré Díaz, Carlota, Blanc, Eric, Napieczynska, Hanna, Langner, Patrick, Werner, Marvin, Walter, Barbara, Wollert-Wulf , Brigitte, Yasuda, Tomoharu, Heuser, Arnd, Beule, Dieter, Mathas, Stephan, Anagnostopoulos, Ioannis, Rosenwald, Andreas, Rajewsky, Klaus, Janz, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013859/
https://www.ncbi.nlm.nih.gov/pubmed/36853944
http://dx.doi.org/10.1073/pnas.2219439120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013859/
https://www.ncbi.nlm.nih.gov/pubmed/36853944
http://dx.doi.org/10.1073/pnas.2219439120

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