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Mouse models of human multiple myeloma subgroups
Multiple myeloma (MM), a tumor of germinal center (GC)-experienced plasma cells, comprises distinct genetic subgroups, such as the t(11;14)/CCND1 and the t(4;14)/MMSET subtype. We have generated genetically defined, subgroup-specific MM models by the GC B cell-specific coactivation of mouse Ccnd1 or...
Autores principales: | Winkler, Wiebke, Farré Díaz, Carlota, Blanc, Eric, Napieczynska, Hanna, Langner, Patrick, Werner, Marvin, Walter, Barbara, Wollert-Wulf , Brigitte, Yasuda, Tomoharu, Heuser, Arnd, Beule, Dieter, Mathas, Stephan, Anagnostopoulos, Ioannis, Rosenwald, Andreas, Rajewsky, Klaus, Janz, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013859/ https://www.ncbi.nlm.nih.gov/pubmed/36853944 http://dx.doi.org/10.1073/pnas.2219439120 |
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