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Long-read sequencing identifies novel structural variations in colorectal cancer

Structural variations (SVs) are a key type of cancer genomic alterations, contributing to oncogenesis and progression of many cancers, including colorectal cancer (CRC). However, SVs in CRC remain difficult to be reliably detected due to limited SV-detection capacity of the commonly used short-read...

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Detalles Bibliográficos
Autores principales: Xu, Luming, Wang, Xingyue, Lu, Xiaohuan, Liang, Fan, Liu, Zhibo, Zhang, Hongyan, Li, Xiaoqiong, Tian, ShaoBo, Wang, Lin, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013895/
https://www.ncbi.nlm.nih.gov/pubmed/36812239
http://dx.doi.org/10.1371/journal.pgen.1010514