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A field-wide assessment of differential expression profiling by high-throughput sequencing reveals widespread bias
We assess inferential quality in the field of differential expression profiling by high-throughput sequencing (HT-seq) based on analysis of datasets submitted from 2008 to 2020 to the NCBI GEO data repository. We take advantage of the parallel differential expression testing over thousands of genes,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013925/ https://www.ncbi.nlm.nih.gov/pubmed/36862747 http://dx.doi.org/10.1371/journal.pbio.3002007 |