Notch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue

Senescence is a key event in the impairment of adipose tissue (AT) function with obesity and aging but the underlying molecular and cellular players remain to be fully defined, particularly with respect to the human AT progenitors. We have found distinct profiles of senescent progenitors based on AT...

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Detalles Bibliográficos
Autores principales: Boulet, Nathalie, Briot, Anaïs, Jargaud, Valentin, Estève, David, Rémaury, Anne, Belles, Chloé, Viana, Pénélope, Fontaine, Jessica, Murphy, Lucie, Déon, Catherine, Guillemot, Marie, Pech, Catherine, Veeranagouda, Yaligara, Didier, Michel, Decaunes, Pauline, Mouisel, Etienne, Carpéné, Christian, Iacovoni, Jason S., Zakaroff‐Girard, Alexia, Grolleau, Jean‐Louis, Galitzky, Jean, Ledoux, Séverine, Guillemot, Jean‐Claude, Bouloumié, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014050/
https://www.ncbi.nlm.nih.gov/pubmed/36617688
http://dx.doi.org/10.1111/acel.13776

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