Cargando…

Neuronal HLH‐30/TFEB modulates peripheral mitochondrial fragmentation to improve thermoresistance in Caenorhabditis elegans

Transcription factor EB (TFEB) is a conserved master transcriptional activator of autophagy and lysosomal genes that modulates organismal lifespan regulation and stress resistance. As neurons can coordinate organism‐wide processes, we investigated the role of neuronal TFEB in stress resistance and l...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Shi Quan, Ryan, Catherine J., Bonal, Dennis M., Mills, Joslyn, Lapierre, Louis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014052/
https://www.ncbi.nlm.nih.gov/pubmed/36419219
http://dx.doi.org/10.1111/acel.13741