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Neuronal HLH‐30/TFEB modulates peripheral mitochondrial fragmentation to improve thermoresistance in Caenorhabditis elegans
Transcription factor EB (TFEB) is a conserved master transcriptional activator of autophagy and lysosomal genes that modulates organismal lifespan regulation and stress resistance. As neurons can coordinate organism‐wide processes, we investigated the role of neuronal TFEB in stress resistance and l...
Autores principales: | Wong, Shi Quan, Ryan, Catherine J., Bonal, Dennis M., Mills, Joslyn, Lapierre, Louis R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014052/ https://www.ncbi.nlm.nih.gov/pubmed/36419219 http://dx.doi.org/10.1111/acel.13741 |
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