Endosomal trafficking protein TBC‐2 modulates stress resistance and lifespan through DAF‐16‐dependent and independent mechanisms

The FOXO transcription factor, DAF‐16, plays an integral role in insulin/IGF‐1 signaling (IIS) and stress response. In conditions of stress or decreased IIS, DAF‐16 moves to the nucleus where it activates genes that promote survival. To gain insight into the role of endosomal trafficking in resistan...

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Detalles Bibliográficos
Autores principales: Traa, Annika, Soo, Sonja K., AlOkda, Abdelrahman, Ko, Bokang, Rocheleau, Christian E., Van Raamsdonk, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014066/
https://www.ncbi.nlm.nih.gov/pubmed/36794357
http://dx.doi.org/10.1111/acel.13762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014066/
https://www.ncbi.nlm.nih.gov/pubmed/36794357
http://dx.doi.org/10.1111/acel.13762

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