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Nrf2-mediated activation of HO-1 is required in the blocking effect of compound K, a ginseng saponin metabolite, against oxidative stress damage in ARPE-19 human retinal pigment epithelial cells

BACKGROUND: The beneficial effects of compound K (CK) on different chronic diseases have been shown to be at least related to antioxidant action. Nevertheless, since its antioxidant activity in human retinal pigment epithelial (RPE) cells is still unknown, here we investigated whether CK alleviates...

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Detalles Bibliográficos
Autores principales: Park, Cheol, Cha, Hee-Jae, Song, Kyoung-Seob, Kim, Heui-Soo, Bang, EunJin, Lee, Hyesook, Jin, Cheng-Yun, Kim, Gi-Young, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014180/
https://www.ncbi.nlm.nih.gov/pubmed/36926611
http://dx.doi.org/10.1016/j.jgr.2022.09.007