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Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals
Several chemicals have been developed owing to the progression of industrialization, among which endocrine-disrupting chemicals (EDCs; essential for plastic production) are used as plasticizers and flame retardants. Plastics have become an essential element in modern life because they provide conven...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014227/ https://www.ncbi.nlm.nih.gov/pubmed/36926605 http://dx.doi.org/10.1016/j.jgr.2022.11.007 |
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author | Jung, Eui-Man Lee, Seung Hyun Lee, Geun-Shik |
author_facet | Jung, Eui-Man Lee, Seung Hyun Lee, Geun-Shik |
author_sort | Jung, Eui-Man |
collection | PubMed |
description | Several chemicals have been developed owing to the progression of industrialization, among which endocrine-disrupting chemicals (EDCs; essential for plastic production) are used as plasticizers and flame retardants. Plastics have become an essential element in modern life because they provide convenience, thus increasing EDCs exposure to humans. EDCs cause adverse effects such as deterioration of reproductive function, cancer, and neurological abnormalities by disrupting the endocrine system and hence are classified as “dangerous substances.” Additionally, they are toxic to various organs but continue to be used. Therefore, it is necessary to review the contamination status of EDCs, select potentially hazardous substances for management, and monitor the safety standards. In addition, it is necessary to discover substances that can protect against EDC toxicity and conduct active research on the protective effects of these substances. According to recent research, Korean Red Ginseng (KRG) exhibits protective effects against several toxicities caused by EDCs to humans. In this review, the effects of EDCs on the human body and the role of KRG in protection against EDC toxicity are discussed. |
format | Online Article Text |
id | pubmed-10014227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-100142272023-03-15 Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals Jung, Eui-Man Lee, Seung Hyun Lee, Geun-Shik J Ginseng Res Review Article Several chemicals have been developed owing to the progression of industrialization, among which endocrine-disrupting chemicals (EDCs; essential for plastic production) are used as plasticizers and flame retardants. Plastics have become an essential element in modern life because they provide convenience, thus increasing EDCs exposure to humans. EDCs cause adverse effects such as deterioration of reproductive function, cancer, and neurological abnormalities by disrupting the endocrine system and hence are classified as “dangerous substances.” Additionally, they are toxic to various organs but continue to be used. Therefore, it is necessary to review the contamination status of EDCs, select potentially hazardous substances for management, and monitor the safety standards. In addition, it is necessary to discover substances that can protect against EDC toxicity and conduct active research on the protective effects of these substances. According to recent research, Korean Red Ginseng (KRG) exhibits protective effects against several toxicities caused by EDCs to humans. In this review, the effects of EDCs on the human body and the role of KRG in protection against EDC toxicity are discussed. Elsevier 2023-03 2022-12-05 /pmc/articles/PMC10014227/ /pubmed/36926605 http://dx.doi.org/10.1016/j.jgr.2022.11.007 Text en © 2022 The Korean Society of Ginseng. Publishing services by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Jung, Eui-Man Lee, Seung Hyun Lee, Geun-Shik Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
title | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
title_full | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
title_fullStr | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
title_full_unstemmed | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
title_short | Protective effects of Korean Red Ginseng against toxicity of endocrine-disrupting chemicals |
title_sort | protective effects of korean red ginseng against toxicity of endocrine-disrupting chemicals |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014227/ https://www.ncbi.nlm.nih.gov/pubmed/36926605 http://dx.doi.org/10.1016/j.jgr.2022.11.007 |
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