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The logical structure of experiments lays the foundation for a theory of reproducibility
The scientific reform movement has proposed openness as a potential remedy to the putative reproducibility or replication crisis. However, the conceptual relationship among openness, replication experiments and results reproducibility has been obscure. We analyse the logical structure of experiments...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014247/ https://www.ncbi.nlm.nih.gov/pubmed/36938532 http://dx.doi.org/10.1098/rsos.221042 |
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author | Buzbas, Erkan O. Devezer, Berna Baumgaertner, Bert |
author_facet | Buzbas, Erkan O. Devezer, Berna Baumgaertner, Bert |
author_sort | Buzbas, Erkan O. |
collection | PubMed |
description | The scientific reform movement has proposed openness as a potential remedy to the putative reproducibility or replication crisis. However, the conceptual relationship among openness, replication experiments and results reproducibility has been obscure. We analyse the logical structure of experiments, define the mathematical notion of idealized experiment and use this notion to advance a theory of reproducibility. Idealized experiments clearly delineate the concepts of replication and results reproducibility, and capture key differences with precision, allowing us to study the relationship among them. We show how results reproducibility varies as a function of the elements of an idealized experiment, the true data-generating mechanism, and the closeness of the replication experiment to an original experiment. We clarify how openness of experiments is related to designing informative replication experiments and to obtaining reproducible results. With formal backing and evidence, we argue that the current ‘crisis’ reflects inadequate attention to a theoretical understanding of results reproducibility. |
format | Online Article Text |
id | pubmed-10014247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-100142472023-03-16 The logical structure of experiments lays the foundation for a theory of reproducibility Buzbas, Erkan O. Devezer, Berna Baumgaertner, Bert R Soc Open Sci Mathematics The scientific reform movement has proposed openness as a potential remedy to the putative reproducibility or replication crisis. However, the conceptual relationship among openness, replication experiments and results reproducibility has been obscure. We analyse the logical structure of experiments, define the mathematical notion of idealized experiment and use this notion to advance a theory of reproducibility. Idealized experiments clearly delineate the concepts of replication and results reproducibility, and capture key differences with precision, allowing us to study the relationship among them. We show how results reproducibility varies as a function of the elements of an idealized experiment, the true data-generating mechanism, and the closeness of the replication experiment to an original experiment. We clarify how openness of experiments is related to designing informative replication experiments and to obtaining reproducible results. With formal backing and evidence, we argue that the current ‘crisis’ reflects inadequate attention to a theoretical understanding of results reproducibility. The Royal Society 2023-03-15 /pmc/articles/PMC10014247/ /pubmed/36938532 http://dx.doi.org/10.1098/rsos.221042 Text en © 2023 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Mathematics Buzbas, Erkan O. Devezer, Berna Baumgaertner, Bert The logical structure of experiments lays the foundation for a theory of reproducibility |
title | The logical structure of experiments lays the foundation for a theory of reproducibility |
title_full | The logical structure of experiments lays the foundation for a theory of reproducibility |
title_fullStr | The logical structure of experiments lays the foundation for a theory of reproducibility |
title_full_unstemmed | The logical structure of experiments lays the foundation for a theory of reproducibility |
title_short | The logical structure of experiments lays the foundation for a theory of reproducibility |
title_sort | logical structure of experiments lays the foundation for a theory of reproducibility |
topic | Mathematics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014247/ https://www.ncbi.nlm.nih.gov/pubmed/36938532 http://dx.doi.org/10.1098/rsos.221042 |
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