BOMA, a machine-learning framework for comparative gene expression analysis across brains and organoids

Our machine-learning framework, brain and organoid manifold alignment (BOMA), first performs a global alignment of developmental gene expression data between brains and organoids. It then applies manifold learning to locally refine the alignment, revealing conserved and specific developmental trajec...

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Detalles Bibliográficos
Autores principales: He, Chenfeng, Kalafut, Noah Cohen, Sandoval, Soraya O., Risgaard, Ryan, Sirois, Carissa L., Yang, Chen, Khullar, Saniya, Suzuki, Marin, Huang, Xiang, Chang, Qiang, Zhao, Xinyu, Sousa, Andre M.M., Wang, Daifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014309/
https://www.ncbi.nlm.nih.gov/pubmed/36936070
http://dx.doi.org/10.1016/j.crmeth.2023.100409

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