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Association of Longitudinal Urinary Metabolic Biomarkers With ADPKD Severity and Response to Metformin in TAME-PKD Clinical Trial Participants

INTRODUCTION: Dysregulated cellular metabolism contributes to autosomal dominant polycystic kidney disease (ADPKD) pathogenesis. The Trial of Administration of Metformin in Polycystic Kidney Disease (TAME-PKD) tested the effects of metformin treatment over 2 years in adult ADPKD patients with mild-m...

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Detalles Bibliográficos
Autores principales:	Hallows, Kenneth R., Abebe, Kaleab Z., Li, Hui, Saitta, Biagio, Althouse, Andrew D., Bae, Kyongtae T., Lalama, Christina M., Miskulin, Dana C., Perrone, Ronald D., Seliger, Stephen L., Watnick, Terry J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014337/ https://www.ncbi.nlm.nih.gov/pubmed/36938071 http://dx.doi.org/10.1016/j.ekir.2022.11.019

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