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Successfully treated case of severe hypothermia secondary to myxedema coma

BACKGROUND: Myxedema coma is an extremely rare but fatal endocrine emergency that requires urgent recognition and treatment. We describe a case of severe hypothermia that rapidly deteriorated to cardiac arrest that was attributed to myxedema coma. CASE PRESENTATION: A 52‐year‐old man without a histo...

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Autores principales: Yamamoto, Hirotsugu, Hongo, Takashi, Nojima, Tsuyoshi, Obara, Takafumi, Kosaki, Yoshinori, Ageta, Kohei, Tsukahara, Kohei, Yumoto, Tetsuya, Nakao, Atsunori, Naito, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014422/
https://www.ncbi.nlm.nih.gov/pubmed/36936740
http://dx.doi.org/10.1002/ams2.828
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author Yamamoto, Hirotsugu
Hongo, Takashi
Nojima, Tsuyoshi
Obara, Takafumi
Kosaki, Yoshinori
Ageta, Kohei
Tsukahara, Kohei
Yumoto, Tetsuya
Nakao, Atsunori
Naito, Hiromichi
author_facet Yamamoto, Hirotsugu
Hongo, Takashi
Nojima, Tsuyoshi
Obara, Takafumi
Kosaki, Yoshinori
Ageta, Kohei
Tsukahara, Kohei
Yumoto, Tetsuya
Nakao, Atsunori
Naito, Hiromichi
author_sort Yamamoto, Hirotsugu
collection PubMed
description BACKGROUND: Myxedema coma is an extremely rare but fatal endocrine emergency that requires urgent recognition and treatment. We describe a case of severe hypothermia that rapidly deteriorated to cardiac arrest that was attributed to myxedema coma. CASE PRESENTATION: A 52‐year‐old man without a history of hypothyroidism was transferred to our emergency department due to coma and profound hypothermia. The patient developed cardiac arrest immediately after hospital arrival but return of spontaneous circulation was achieved shortly after resuscitation. The patient was noted to have generalized, nonpitting edema, dry skin, severe respiratory acidosis, hyponatremia, and elevated creatinine kinase, which was indicative of hypothyroidism. Myxedema coma was confirmed by a thyroid profile. The patient was successfully treated with intravenous levothyroxine and glucocorticoid. CONCLUSION: Although myxedema coma is a rare cause of severe hypothermia, emergency physicians should be familiar with its clinical features and management.
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spelling pubmed-100144222023-03-16 Successfully treated case of severe hypothermia secondary to myxedema coma Yamamoto, Hirotsugu Hongo, Takashi Nojima, Tsuyoshi Obara, Takafumi Kosaki, Yoshinori Ageta, Kohei Tsukahara, Kohei Yumoto, Tetsuya Nakao, Atsunori Naito, Hiromichi Acute Med Surg Case Report BACKGROUND: Myxedema coma is an extremely rare but fatal endocrine emergency that requires urgent recognition and treatment. We describe a case of severe hypothermia that rapidly deteriorated to cardiac arrest that was attributed to myxedema coma. CASE PRESENTATION: A 52‐year‐old man without a history of hypothyroidism was transferred to our emergency department due to coma and profound hypothermia. The patient developed cardiac arrest immediately after hospital arrival but return of spontaneous circulation was achieved shortly after resuscitation. The patient was noted to have generalized, nonpitting edema, dry skin, severe respiratory acidosis, hyponatremia, and elevated creatinine kinase, which was indicative of hypothyroidism. Myxedema coma was confirmed by a thyroid profile. The patient was successfully treated with intravenous levothyroxine and glucocorticoid. CONCLUSION: Although myxedema coma is a rare cause of severe hypothermia, emergency physicians should be familiar with its clinical features and management. John Wiley and Sons Inc. 2023-03-14 /pmc/articles/PMC10014422/ /pubmed/36936740 http://dx.doi.org/10.1002/ams2.828 Text en © 2023 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Yamamoto, Hirotsugu
Hongo, Takashi
Nojima, Tsuyoshi
Obara, Takafumi
Kosaki, Yoshinori
Ageta, Kohei
Tsukahara, Kohei
Yumoto, Tetsuya
Nakao, Atsunori
Naito, Hiromichi
Successfully treated case of severe hypothermia secondary to myxedema coma
title Successfully treated case of severe hypothermia secondary to myxedema coma
title_full Successfully treated case of severe hypothermia secondary to myxedema coma
title_fullStr Successfully treated case of severe hypothermia secondary to myxedema coma
title_full_unstemmed Successfully treated case of severe hypothermia secondary to myxedema coma
title_short Successfully treated case of severe hypothermia secondary to myxedema coma
title_sort successfully treated case of severe hypothermia secondary to myxedema coma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014422/
https://www.ncbi.nlm.nih.gov/pubmed/36936740
http://dx.doi.org/10.1002/ams2.828
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