Cargando…

EGCG identified as an autophagy inducer for rosacea therapy

Background: Rosacea is a common facial skin inflammatory disease featured by hyperactivation of mTORC1 signaling in the epidermis. Due to unclear pathogenesis, the effective treatment options for rosacea remain limited. Methods: Weighted gene co-expression network analysis (WGCNA) analyzed the relat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Lei, Zhong, Yun, Wang, Yaling, Deng, Zhili, Huang, Yingxue, Wang, Qian, Xie, Hongfu, Zhang, Yiya, Li, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014537/ https://www.ncbi.nlm.nih.gov/pubmed/36937834 http://dx.doi.org/10.3389/fphar.2023.1092473

Ejemplares similares

Efficacy and safety of antibiotic agents in the treatment of rosacea: a systemic network meta-analysis
por: Xiao, Wenqin, et al.
Publicado: (2023)

Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in AD and Rosacea
por: Zhang, Huaxiong, et al.
Publicado: (2021)

Multi-Transcriptomic Analysis and Experimental Validation Implicate a Central Role of STAT3 in Skin Barrier Dysfunction Induced Aggravation of Rosacea
por: Wang, Yaling, et al.
Publicado: (2022)

Whole genome sequencing identifies genetic variants associated with neurogenic inflammation in rosacea
por: Deng, Zhili, et al.
Publicado: (2023)

Skincare Habits and Rosacea in 3,439 Chinese Adolescents: A University-based Cross-sectional Study
por: ZUO, Zhihong, et al.
Publicado: (2020)

Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases
por: Zhang, Yiya, et al.
Publicado: (2022)

Targeting Aquaporin-3 Attenuates Skin Inflammation in Rosacea
por: Chen, Mengting, et al.
Publicado: (2023)

Aberrant amino acid metabolism promotes neurovascular reactivity in rosacea
por: Liu, Tangxiele, et al.
Publicado: (2022)

The Rosacea-specific Quality-of-Life instrument (RosQol): Revision and validation among Chinese patients
por: Deng, Yuxuan, et al.
Publicado: (2018)

mTORC1-Mediated Angiogenesis is Required for the Development of Rosacea
por: Peng, Qinqin, et al.
Publicado: (2021)

EGCG protects the mouse brain against cerebral ischemia/reperfusion injury by suppressing autophagy via the AKT/AMPK/mTOR phosphorylation pathway
por: Wang, Li, et al.
Publicado: (2022)

Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China
por: Chen, Mengting, et al.
Publicado: (2021)

Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
por: Wang, Ben, et al.
Publicado: (2020)

A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea
por: Deng, Zhili, et al.
Publicado: (2021)

Health Related Quality of Life of Rosacea Patients in China Assessed by Dermatology Life Quality Index and Willingness to Pay
por: Huang, Yaqun, et al.
Publicado: (2022)

An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis
por: Hung, Sze Wan, et al.
Publicado: (2021)

Mediation roles of neutrophils and high-density lipoprotein (HDL) on the relationship between HLA-DQB1 and rosacea
por: Xiao, Wenqin, et al.
Publicado: (2022)

Willingness-to-Pay and Benefit–Cost Analysis of Botulinum Toxin for the Treatment of Rosacea in China: Findings from a Web-Based Survey
por: Yang, Xizhao, et al.
Publicado: (2021)

LC–MS Based Metabolomics Study of the Effects of EGCG on A549 Cells
por: Pan, Tingyu, et al.
Publicado: (2021)

Relationship Between Tea Drinking Behaviour and Rosacea: A Clinical Case-control Study
por: WANG, Ben, et al.
Publicado: (2021)

A novel multi-layer perceptron model for assessing the diagnostic value of non-invasive imaging instruments for rosacea
por: Huang, Yingxue, et al.
Publicado: (2022)

A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study
por: Zhao, Zhixiang, et al.
Publicado: (2021)

EGCG Reduces Obesity and White Adipose Tissue Gain Partly Through AMPK Activation in Mice
por: Li, Fang, et al.
Publicado: (2018)

Haplopelma hainanum venom induces inflammatory skin lesions
por: Deng, Zhili, et al.
Publicado: (2020)

Keratinocyte-Immune Cell Crosstalk in a STAT1-Mediated Pathway: Novel Insights Into Rosacea Pathogenesis
por: Deng, Zhili, et al.
Publicado: (2021)

Clinical characteristics and epidermal barrier function of papulopustular rosacea: A comparison study with acne vulgaris
por: Zhou, Maosong, et al.
Publicado: (2016)

Amino Acid Degrading Enzymes and Autophagy in Cancer Therapy
por: Wang, Ziyu, et al.
Publicado: (2021)

Combination of an Autophagy Inducer and an Autophagy Inhibitor: A Smarter Strategy Emerging in Cancer Therapy
por: Liu, Ting, et al.
Publicado: (2020)

TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea
por: Huang, Yaqun, et al.
Publicado: (2023)

Bee Pollen Polysaccharide From Rosa rugosa Thunb. (Rosaceae) Promotes Pancreatic β-Cell Proliferation and Insulin Secretion
por: Yang, Siwen, et al.
Publicado: (2021)

Platelet factor 4 inhibits human hair follicle growth and promotes androgen receptor expression in human dermal papilla cells
por: Sha, Ke, et al.
Publicado: (2020)

Vitamin K2 Can Rescue the Dexamethasone-Induced Downregulation of Osteoblast Autophagy and Mitophagy Thereby Restoring Osteoblast Function In Vitro and In Vivo
por: Chen, Liang, et al.
Publicado: (2020)

Progress in the Mechanism of Autophagy and Traditional Chinese Medicine Herb Involved in Dementia
por: Tao, Pengyu, et al.
Publicado: (2022)

Rhynchophylline Attenuates Senescence of Endothelial Progenitor Cells by Enhancing Autophagy
por: Lin, Lin, et al.
Publicado: (2020)

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy
por: Luo, Li-Fei, et al.
Publicado: (2021)

Insight Into the Prospects for RNAi Therapy of Cancer
por: Tian, Zhili, et al.
Publicado: (2021)

JZTX-V Targets the Voltage Sensor in Kv4.2 to Inhibit I(to) Potassium Channels in Cardiomyocytes
por: Zhang, Yiya, et al.
Publicado: (2019)

Exogenous Hydrogen Sulfide Ameliorates Diabetic Myocardial Fibrosis by Inhibiting Cell Aging Through SIRT6/AMPK Autophagy
por: Li, Yaling, et al.
Publicado: (2020)

Bruceae Fructus Oil Inhibits Triple-Negative Breast Cancer by Restraining Autophagy: Dependence on the Gut Microbiota-Mediated Amino Acid Regulation
por: Su, Jiyan, et al.
Publicado: (2021)

Autophagy Modulators From Chinese Herbal Medicines: Mechanisms and Therapeutic Potentials for Asthma
por: Zhang, Yun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5qogih51jeubksibb88vd8msu8