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Comparative pharmacokinetics of four major compounds after oral administration of Mori Cortex total flavonoid extract in normal and diabetic rats

Introduction: Mori Cortex has been used in traditional Chinese Medicine as an antidiabetic agent. The aim of this study was to establish a UPLC-MS/MS method for simultaneous determination of morin, morusin, umbelliferone and mulberroside A in rat plasma and investigate the pharmacokinetics differenc...

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Detalles Bibliográficos
Autores principales: Xiong, Shan, Li, Xiaofan, Chu, Haiping, Deng, Zhipeng, Sun, Linying, Liu, Jia, Mu, Yanling, Yao, Qingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014546/
https://www.ncbi.nlm.nih.gov/pubmed/36937873
http://dx.doi.org/10.3389/fphar.2023.1148332