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Inflammasome activation and formation of ASC specks in patients with juvenile idiopathic arthritis

OBJECTIVE: The formation of large intracellular protein aggregates of the inflammasome adaptor ASC is a hallmark of inflammasome activation and characteristic of autoinflammation. Inflammasome activated cells release the highly proinflammatory cytokine IL-1β in addition to ASC specks into the extrac...

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Detalles Bibliográficos
Autores principales:	Wittmann, Nico, Mishra, Neha, Gramenz, Jana, Kuthning, Daniela, Behrendt, Ann-Kathrin, Bossaller, Lukas, Meyer-Bahlburg, Almut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014801/ https://www.ncbi.nlm.nih.gov/pubmed/36936231 http://dx.doi.org/10.3389/fmed.2023.1063772

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