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A laser-induced mouse model of progressive retinal degeneration with central sparing displays features of parafoveal geographic atrophy

There are no disease-modifying treatments available for geographic atrophy (GA), the advanced form of dry age-related macular degeneration. Current murine models fail to fully recapitulate the features of GA and thus hinder drug discovery. Here we describe a novel mouse model of retinal degeneration...

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Detalles Bibliográficos
Autores principales:	Khan, Adnan H., Soundara Pandi, Sudha Priya, Scott, Jennifer A., Sánchez-Bretaño, Aida, Lynn, Savannah A., Ratnayaka, J. Arjuna, Teeling, Jessica L., Lotery, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014848/ https://www.ncbi.nlm.nih.gov/pubmed/36918701 http://dx.doi.org/10.1038/s41598-023-31392-3

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