Cargando…

Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders

Lipid metabolism disorders (LMD) can cause a series of metabolic diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD) and atherosclerosis (AS). Its development is caused by more pathogenic factors, among which intestinal flora dysbiosis is considered to be an import...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Min, Shi, Wei, Huang, Yefang, Wu, Yeke, Wu, Keming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014879/
https://www.ncbi.nlm.nih.gov/pubmed/36937840
http://dx.doi.org/10.3389/fphar.2023.1134430
_version_ 1784907094709764096
author Liu, Min
Shi, Wei
Huang, Yefang
Wu, Yeke
Wu, Keming
author_facet Liu, Min
Shi, Wei
Huang, Yefang
Wu, Yeke
Wu, Keming
author_sort Liu, Min
collection PubMed
description Lipid metabolism disorders (LMD) can cause a series of metabolic diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD) and atherosclerosis (AS). Its development is caused by more pathogenic factors, among which intestinal flora dysbiosis is considered to be an important pathogenic mechanism of LMD. In recent years, the research on intestinal flora has made great progress, opening up new perspectives on the occurrence and therapeutic effects of diseases. With its complex composition and wide range of targets, traditional Chinese medicine (TCM) is widely used to prevent and treat LMD. This review takes intestinal flora as a target, elaborates on the scientific connotation of TCM in the treatment of LMD, updates the therapeutic thinking of LMD, and provides a reference for clinical diagnosis and treatment.
format Online
Article
Text
id pubmed-10014879
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-100148792023-03-16 Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders Liu, Min Shi, Wei Huang, Yefang Wu, Yeke Wu, Keming Front Pharmacol Pharmacology Lipid metabolism disorders (LMD) can cause a series of metabolic diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD) and atherosclerosis (AS). Its development is caused by more pathogenic factors, among which intestinal flora dysbiosis is considered to be an important pathogenic mechanism of LMD. In recent years, the research on intestinal flora has made great progress, opening up new perspectives on the occurrence and therapeutic effects of diseases. With its complex composition and wide range of targets, traditional Chinese medicine (TCM) is widely used to prevent and treat LMD. This review takes intestinal flora as a target, elaborates on the scientific connotation of TCM in the treatment of LMD, updates the therapeutic thinking of LMD, and provides a reference for clinical diagnosis and treatment. Frontiers Media S.A. 2023-03-01 /pmc/articles/PMC10014879/ /pubmed/36937840 http://dx.doi.org/10.3389/fphar.2023.1134430 Text en Copyright © 2023 Liu, Shi, Huang, Wu and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Liu, Min
Shi, Wei
Huang, Yefang
Wu, Yeke
Wu, Keming
Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders
title Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders
title_full Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders
title_fullStr Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders
title_full_unstemmed Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders
title_short Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders
title_sort intestinal flora: a new target for traditional chinese medicine to improve lipid metabolism disorders
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014879/
https://www.ncbi.nlm.nih.gov/pubmed/36937840
http://dx.doi.org/10.3389/fphar.2023.1134430
work_keys_str_mv AT liumin intestinalfloraanewtargetfortraditionalchinesemedicinetoimprovelipidmetabolismdisorders
AT shiwei intestinalfloraanewtargetfortraditionalchinesemedicinetoimprovelipidmetabolismdisorders
AT huangyefang intestinalfloraanewtargetfortraditionalchinesemedicinetoimprovelipidmetabolismdisorders
AT wuyeke intestinalfloraanewtargetfortraditionalchinesemedicinetoimprovelipidmetabolismdisorders
AT wukeming intestinalfloraanewtargetfortraditionalchinesemedicinetoimprovelipidmetabolismdisorders