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Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders
Lipid metabolism disorders (LMD) can cause a series of metabolic diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD) and atherosclerosis (AS). Its development is caused by more pathogenic factors, among which intestinal flora dysbiosis is considered to be an import...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014879/ https://www.ncbi.nlm.nih.gov/pubmed/36937840 http://dx.doi.org/10.3389/fphar.2023.1134430 |
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author | Liu, Min Shi, Wei Huang, Yefang Wu, Yeke Wu, Keming |
author_facet | Liu, Min Shi, Wei Huang, Yefang Wu, Yeke Wu, Keming |
author_sort | Liu, Min |
collection | PubMed |
description | Lipid metabolism disorders (LMD) can cause a series of metabolic diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD) and atherosclerosis (AS). Its development is caused by more pathogenic factors, among which intestinal flora dysbiosis is considered to be an important pathogenic mechanism of LMD. In recent years, the research on intestinal flora has made great progress, opening up new perspectives on the occurrence and therapeutic effects of diseases. With its complex composition and wide range of targets, traditional Chinese medicine (TCM) is widely used to prevent and treat LMD. This review takes intestinal flora as a target, elaborates on the scientific connotation of TCM in the treatment of LMD, updates the therapeutic thinking of LMD, and provides a reference for clinical diagnosis and treatment. |
format | Online Article Text |
id | pubmed-10014879 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100148792023-03-16 Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders Liu, Min Shi, Wei Huang, Yefang Wu, Yeke Wu, Keming Front Pharmacol Pharmacology Lipid metabolism disorders (LMD) can cause a series of metabolic diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD) and atherosclerosis (AS). Its development is caused by more pathogenic factors, among which intestinal flora dysbiosis is considered to be an important pathogenic mechanism of LMD. In recent years, the research on intestinal flora has made great progress, opening up new perspectives on the occurrence and therapeutic effects of diseases. With its complex composition and wide range of targets, traditional Chinese medicine (TCM) is widely used to prevent and treat LMD. This review takes intestinal flora as a target, elaborates on the scientific connotation of TCM in the treatment of LMD, updates the therapeutic thinking of LMD, and provides a reference for clinical diagnosis and treatment. Frontiers Media S.A. 2023-03-01 /pmc/articles/PMC10014879/ /pubmed/36937840 http://dx.doi.org/10.3389/fphar.2023.1134430 Text en Copyright © 2023 Liu, Shi, Huang, Wu and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Liu, Min Shi, Wei Huang, Yefang Wu, Yeke Wu, Keming Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders |
title | Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders |
title_full | Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders |
title_fullStr | Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders |
title_full_unstemmed | Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders |
title_short | Intestinal flora: A new target for traditional Chinese medicine to improve lipid metabolism disorders |
title_sort | intestinal flora: a new target for traditional chinese medicine to improve lipid metabolism disorders |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014879/ https://www.ncbi.nlm.nih.gov/pubmed/36937840 http://dx.doi.org/10.3389/fphar.2023.1134430 |
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