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BRD9-mediated chromatin remodeling suppresses osteoclastogenesis through negative feedback mechanism
Bromodomain-containing protein 9 (BRD9), a component of non-canonical BAF chromatin remodeling complex, has been identified as a critical therapeutic target in hematological diseases. Despite the hematopoietic origin of osteoclasts, the role of BRD9 in osteoclastogenesis and bone diseases remains un...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014883/ https://www.ncbi.nlm.nih.gov/pubmed/36918560 http://dx.doi.org/10.1038/s41467-023-37116-5 |