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BRD9-mediated chromatin remodeling suppresses osteoclastogenesis through negative feedback mechanism

Bromodomain-containing protein 9 (BRD9), a component of non-canonical BAF chromatin remodeling complex, has been identified as a critical therapeutic target in hematological diseases. Despite the hematopoietic origin of osteoclasts, the role of BRD9 in osteoclastogenesis and bone diseases remains un...

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Detalles Bibliográficos
Autores principales: Du, Jiahui, Liu, Yili, Wu, Xiaolin, Sun, Jinrui, Shi, Junfeng, Zhang, Hongming, Zheng, Ao, Zhou, Mingliang, Jiang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014883/
https://www.ncbi.nlm.nih.gov/pubmed/36918560
http://dx.doi.org/10.1038/s41467-023-37116-5