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1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity

Superoxide (O(2)(·−)) is the primary reactive oxygen species in mammal cells. Detecting superoxide is crucial for understanding redox signaling but remains challenging. Herein, we introduce a class of activity-based sensing probes. The probes utilize 1,2,4,5-tetrazine as a superoxide-responsive trig...

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Detalles Bibliográficos
Autores principales: Jiang, Xuefeng, Li, Min, Wang, Yule, Wang, Chao, Wang, Yingchao, Shen, Tianruo, Shen, Lili, Liu, Xiaogang, Wang, Yi, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10014963/
https://www.ncbi.nlm.nih.gov/pubmed/36918556
http://dx.doi.org/10.1038/s41467-023-37121-8

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