Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates

Detalles Bibliográficos
Autores principales: Uffelmann, Emil, Posthuma, Danielle, Peyrot, Wouter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Matters Arising
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015046/
https://www.ncbi.nlm.nih.gov/pubmed/36918594
http://dx.doi.org/10.1038/s41598-023-29428-9
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author Uffelmann, Emil
Posthuma, Danielle
Peyrot, Wouter J.
author_facet Uffelmann, Emil
Posthuma, Danielle
Peyrot, Wouter J.
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spelling pubmed-100150462023-03-16 Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates Uffelmann, Emil Posthuma, Danielle Peyrot, Wouter J. Sci Rep Matters Arising Nature Publishing Group UK 2023-03-14 /pmc/articles/PMC10015046/ /pubmed/36918594 http://dx.doi.org/10.1038/s41598-023-29428-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Matters Arising
Uffelmann, Emil
Posthuma, Danielle
Peyrot, Wouter J.
Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
title Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
title_full Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
title_fullStr Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
title_full_unstemmed Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
title_short Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
title_sort genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
topic Matters Arising
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015046/
https://www.ncbi.nlm.nih.gov/pubmed/36918594
http://dx.doi.org/10.1038/s41598-023-29428-9
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