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The platelet pannexin 1-IL-1β axis orchestrates pancreatic ductal adenocarcinoma invasion and metastasis

We aimed to investigate the protumor mechanisms of platelets in pancreatic ductal adenocarcinoma (PDAC). Serum samples were collected from 656 PDAC patients and 3105 healthy people, and a Panx1 knockout tumor model and an adoptive platelet transfusion mouse model were established. We showed that the...

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Detalles Bibliográficos
Autores principales:	Li, Hao, Jiang, Wang, Zhang, Shi-Rong, Li, Peng-Cheng, Li, Tian-Jiao, Jin, Wei, Xu, Hua-Xiang, Yu, Xian-Jun, Liu, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015141/ https://www.ncbi.nlm.nih.gov/pubmed/36922676 http://dx.doi.org/10.1038/s41388-023-02647-0

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