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Impact of epilepsy on the risk of hospital-treated injuries in Finnish children
OBJECTIVES: To study the effect of epilepsy on the risk of injury in children. METHODS: All first-born singleton children (n = 133055) born in 2001 – 2006 in Finland were included. Data was collected from national registers up to the first hospital-treated injury during the five years following the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015441/ https://www.ncbi.nlm.nih.gov/pubmed/36935841 http://dx.doi.org/10.1016/j.ebr.2023.100587 |
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author | Ripatti, Liisi Puustinen, Laura Rautava, Päivi Koivisto, Mari Haataja, Leena |
author_facet | Ripatti, Liisi Puustinen, Laura Rautava, Päivi Koivisto, Mari Haataja, Leena |
author_sort | Ripatti, Liisi |
collection | PubMed |
description | OBJECTIVES: To study the effect of epilepsy on the risk of injury in children. METHODS: All first-born singleton children (n = 133055) born in 2001 – 2006 in Finland were included. Data was collected from national registers up to the first hospital-treated injury during the five years following the onset of epilepsy. Four matched controls were chosen for every subject. RESULTS: Epilepsy had been diagnosed in 0.66 % of children. During follow-up, 12 % of 884 children with epilepsy and 9 % of 3536 controls were hospitalized for injuries (HR 1.387 [95 % CI 1.115 – 1.725]; p = 0.0033). Risk for injuries was higher in boys than girls (p = 0.0057). Mean age at the first injury was 6.8 years (SD 3.3, median 7, range 0–13) in subjects and 7.2 years (SD 3.2, median 8, range 1–13) in controls (p = 0.272). The rate of hospitalization did not differ according to the type of epilepsy. The risks of subjects compared to controls were not significantly different concerning the nature of injury or survival. CONCLUSIONS: Children with epilepsy are at increased risk for hospital-treated injuries. The spectrum of injuries and the risk for death due to injuries are not different in children with and without epilepsy. |
format | Online Article Text |
id | pubmed-10015441 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-100154412023-03-16 Impact of epilepsy on the risk of hospital-treated injuries in Finnish children Ripatti, Liisi Puustinen, Laura Rautava, Päivi Koivisto, Mari Haataja, Leena Epilepsy Behav Rep Article OBJECTIVES: To study the effect of epilepsy on the risk of injury in children. METHODS: All first-born singleton children (n = 133055) born in 2001 – 2006 in Finland were included. Data was collected from national registers up to the first hospital-treated injury during the five years following the onset of epilepsy. Four matched controls were chosen for every subject. RESULTS: Epilepsy had been diagnosed in 0.66 % of children. During follow-up, 12 % of 884 children with epilepsy and 9 % of 3536 controls were hospitalized for injuries (HR 1.387 [95 % CI 1.115 – 1.725]; p = 0.0033). Risk for injuries was higher in boys than girls (p = 0.0057). Mean age at the first injury was 6.8 years (SD 3.3, median 7, range 0–13) in subjects and 7.2 years (SD 3.2, median 8, range 1–13) in controls (p = 0.272). The rate of hospitalization did not differ according to the type of epilepsy. The risks of subjects compared to controls were not significantly different concerning the nature of injury or survival. CONCLUSIONS: Children with epilepsy are at increased risk for hospital-treated injuries. The spectrum of injuries and the risk for death due to injuries are not different in children with and without epilepsy. Elsevier 2023-01-16 /pmc/articles/PMC10015441/ /pubmed/36935841 http://dx.doi.org/10.1016/j.ebr.2023.100587 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ripatti, Liisi Puustinen, Laura Rautava, Päivi Koivisto, Mari Haataja, Leena Impact of epilepsy on the risk of hospital-treated injuries in Finnish children |
title | Impact of epilepsy on the risk of hospital-treated injuries in Finnish children |
title_full | Impact of epilepsy on the risk of hospital-treated injuries in Finnish children |
title_fullStr | Impact of epilepsy on the risk of hospital-treated injuries in Finnish children |
title_full_unstemmed | Impact of epilepsy on the risk of hospital-treated injuries in Finnish children |
title_short | Impact of epilepsy on the risk of hospital-treated injuries in Finnish children |
title_sort | impact of epilepsy on the risk of hospital-treated injuries in finnish children |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015441/ https://www.ncbi.nlm.nih.gov/pubmed/36935841 http://dx.doi.org/10.1016/j.ebr.2023.100587 |
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