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Impact of epilepsy on the risk of hospital-treated injuries in Finnish children

OBJECTIVES: To study the effect of epilepsy on the risk of injury in children. METHODS: All first-born singleton children (n = 133055) born in 2001 – 2006 in Finland were included. Data was collected from national registers up to the first hospital-treated injury during the five years following the...

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Autores principales: Ripatti, Liisi, Puustinen, Laura, Rautava, Päivi, Koivisto, Mari, Haataja, Leena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015441/
https://www.ncbi.nlm.nih.gov/pubmed/36935841
http://dx.doi.org/10.1016/j.ebr.2023.100587
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author Ripatti, Liisi
Puustinen, Laura
Rautava, Päivi
Koivisto, Mari
Haataja, Leena
author_facet Ripatti, Liisi
Puustinen, Laura
Rautava, Päivi
Koivisto, Mari
Haataja, Leena
author_sort Ripatti, Liisi
collection PubMed
description OBJECTIVES: To study the effect of epilepsy on the risk of injury in children. METHODS: All first-born singleton children (n = 133055) born in 2001 – 2006 in Finland were included. Data was collected from national registers up to the first hospital-treated injury during the five years following the onset of epilepsy. Four matched controls were chosen for every subject. RESULTS: Epilepsy had been diagnosed in 0.66 % of children. During follow-up, 12 % of 884 children with epilepsy and 9 % of 3536 controls were hospitalized for injuries (HR 1.387 [95 % CI 1.115 – 1.725]; p = 0.0033). Risk for injuries was higher in boys than girls (p = 0.0057). Mean age at the first injury was 6.8 years (SD 3.3, median 7, range 0–13) in subjects and 7.2 years (SD 3.2, median 8, range 1–13) in controls (p = 0.272). The rate of hospitalization did not differ according to the type of epilepsy. The risks of subjects compared to controls were not significantly different concerning the nature of injury or survival. CONCLUSIONS: Children with epilepsy are at increased risk for hospital-treated injuries. The spectrum of injuries and the risk for death due to injuries are not different in children with and without epilepsy.
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spelling pubmed-100154412023-03-16 Impact of epilepsy on the risk of hospital-treated injuries in Finnish children Ripatti, Liisi Puustinen, Laura Rautava, Päivi Koivisto, Mari Haataja, Leena Epilepsy Behav Rep Article OBJECTIVES: To study the effect of epilepsy on the risk of injury in children. METHODS: All first-born singleton children (n = 133055) born in 2001 – 2006 in Finland were included. Data was collected from national registers up to the first hospital-treated injury during the five years following the onset of epilepsy. Four matched controls were chosen for every subject. RESULTS: Epilepsy had been diagnosed in 0.66 % of children. During follow-up, 12 % of 884 children with epilepsy and 9 % of 3536 controls were hospitalized for injuries (HR 1.387 [95 % CI 1.115 – 1.725]; p = 0.0033). Risk for injuries was higher in boys than girls (p = 0.0057). Mean age at the first injury was 6.8 years (SD 3.3, median 7, range 0–13) in subjects and 7.2 years (SD 3.2, median 8, range 1–13) in controls (p = 0.272). The rate of hospitalization did not differ according to the type of epilepsy. The risks of subjects compared to controls were not significantly different concerning the nature of injury or survival. CONCLUSIONS: Children with epilepsy are at increased risk for hospital-treated injuries. The spectrum of injuries and the risk for death due to injuries are not different in children with and without epilepsy. Elsevier 2023-01-16 /pmc/articles/PMC10015441/ /pubmed/36935841 http://dx.doi.org/10.1016/j.ebr.2023.100587 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ripatti, Liisi
Puustinen, Laura
Rautava, Päivi
Koivisto, Mari
Haataja, Leena
Impact of epilepsy on the risk of hospital-treated injuries in Finnish children
title Impact of epilepsy on the risk of hospital-treated injuries in Finnish children
title_full Impact of epilepsy on the risk of hospital-treated injuries in Finnish children
title_fullStr Impact of epilepsy on the risk of hospital-treated injuries in Finnish children
title_full_unstemmed Impact of epilepsy on the risk of hospital-treated injuries in Finnish children
title_short Impact of epilepsy on the risk of hospital-treated injuries in Finnish children
title_sort impact of epilepsy on the risk of hospital-treated injuries in finnish children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015441/
https://www.ncbi.nlm.nih.gov/pubmed/36935841
http://dx.doi.org/10.1016/j.ebr.2023.100587
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