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A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation
Chronic unresolving inflammation is emerging as a key underlying pathological feature of many if not most diseases ranging from autoimmune conditions to cardiometabolic and neurological disorders. Dysregulated immune and inflammasome activation is thought to be the central driver of unresolving infl...
Autores principales: | Jayabalan, Nanthini, Oronsky, Bryan, Cabrales, Pedro, Reid, Tony, Caroen, Scott, Johnson, Aishwarya M., Birch, Natalia A., O’Sullivan, John D., Gordon, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015535/ https://www.ncbi.nlm.nih.gov/pubmed/36920652 http://dx.doi.org/10.1007/s40265-023-01838-z |
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