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The pyridazine heterocycle in molecular recognition and drug discovery
The pyridazine ring is endowed with unique physicochemical properties, characterized by weak basicity, a high dipole moment that subtends π-π stacking interactions and robust, dual hydrogen-bonding capacity that can be of importance in drug-target interactions. These properties contribute to unique...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015555/ https://www.ncbi.nlm.nih.gov/pubmed/37362319 http://dx.doi.org/10.1007/s00044-023-03035-9 |