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Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma

BACKGROUND: The prognostic impact of EGFR mutation as major targetable somatic gene variant on lung adenocarcinoma is controversial. KRAS is another major somatic variant in lung adenocarcinoma, and a therapeutic agent for KRAS G12C became available in clinical settings. These mutations represent cl...

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Detalles Bibliográficos
Autores principales:	Ito, Masaoki, Miyata, Yoshihiro, Kushitani, Kei, Ueda, Daisuke, Takeshima, Yukio, Okada, Morihito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015689/ https://www.ncbi.nlm.nih.gov/pubmed/36918771 http://dx.doi.org/10.1186/s12885-023-10716-6

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