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Ste20-Like Kinase TAOK1 Positively Regulates Antiviral Responses by Controlling the TBK1-IRF3 Signaling Axis
The cytosolic viral nucleic acid-sensing pathways converge on the protein kinase TANK-binding kinase 1 (TBK1) and the transcription factor interferon (IFN)-regulatory factor 3 (IRF3) to induce type I IFN production and antiviral immune responses. However, the mechanism that triggers the binding of T...
Autores principales: | Luo, Xiaogang, Ji, Ruihua, Liu, Qianru, Xiao, Xiaoxue, Song, Wengang, An, Huazhang, Li, Yingke, Zhou, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015707/ https://www.ncbi.nlm.nih.gov/pubmed/36649698 http://dx.doi.org/10.1159/000526324 |
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