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Ste20-Like Kinase TAOK1 Positively Regulates Antiviral Responses by Controlling the TBK1-IRF3 Signaling Axis

The cytosolic viral nucleic acid-sensing pathways converge on the protein kinase TANK-binding kinase 1 (TBK1) and the transcription factor interferon (IFN)-regulatory factor 3 (IRF3) to induce type I IFN production and antiviral immune responses. However, the mechanism that triggers the binding of T...

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Detalles Bibliográficos
Autores principales: Luo, Xiaogang, Ji, Ruihua, Liu, Qianru, Xiao, Xiaoxue, Song, Wengang, An, Huazhang, Li, Yingke, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015707/
https://www.ncbi.nlm.nih.gov/pubmed/36649698
http://dx.doi.org/10.1159/000526324

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