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Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments

The alphaherpesvirus pseudorabies virus (PRV) is the causative agent of pseudorabies, responsible for severe economic losses to the swine industry worldwide. The interferon-inducible GTPase guanylate-binding protein 1 (GBP1) exhibits antiviral immunity. Our findings show that there is a robust upreg...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaohua, Du, Qian, Chen, Guiyuan, Jiang, Yiyuan, Huang, Kai, Li, Linghao, Tong, Dewen, Huang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015811/ https://www.ncbi.nlm.nih.gov/pubmed/36918936 http://dx.doi.org/10.1186/s13567-023-01154-0

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