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A positive feedback loop driven by fibronectin and IL-1β sustains the inflammatory microenvironment in breast cancer

Inflammatory alterations of the extracellular matrix shape the tumor microenvironment and promote all stages of carcinogenesis. This study aims to determine the impact of cellular fibronectin on inflammatory facets of tumor-associated macrophages (TAMs) in breast cancer. Cellular fibronectin (FN) ha...

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Detalles Bibliográficos
Autores principales: Tunali, Gurcan, Yanik, Hamdullah, Ozturk, Suleyman Can, Demirkol-Canli, Secil, Efthymiou, Georgios, Yilmaz, Kerim Bora, Van Obberghen-Schilling, Ellen, Esendagli, Gunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015813/
https://www.ncbi.nlm.nih.gov/pubmed/36922898
http://dx.doi.org/10.1186/s13058-023-01629-0