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Codelivery of BCL2 and MCL1 Inhibitors Enabled by Phenylboronic Acid‐Functionalized Polypeptide Nanovehicles for Synergetic and Potent Therapy of Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is the most refractory hematologic malignancy characterized by acute onset, rapid progression, and high recurrence rate. Here, codelivery of BCL2 (ABT199) and MCL1 (TW37) inhibitors using phenylboronic acid‐functionalized polypeptide nanovehicles to achieve synergetic an...
Autores principales: | Xie, Jiguo, Zhao, Xiaofei, Zhang, Peng, Zhang, Yueyue, Cheng, Ru, Zhong, Zhiyuan, Deng, Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015845/ https://www.ncbi.nlm.nih.gov/pubmed/36683178 http://dx.doi.org/10.1002/advs.202204866 |
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