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The Impact of the Cellular Environment and Aging on Modeling Alzheimer's Disease in 3D Cell Culture Models

Creating a cellular model of Alzheimer's disease (AD) that accurately recapitulates disease pathology has been a longstanding challenge. Recent studies showed that human AD neural cells, integrated into three‐dimensional (3D) hydrogel matrix, display key features of AD neuropathology. Like in t...

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Detalles Bibliográficos
Autores principales: Hebisch, Matthias, Klostermeier, Stefanie, Wolf, Katharina, Boccaccini, Aldo R., Wolf, Stephan E., Tanzi, Rudolph E., Kim, Doo Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015857/
https://www.ncbi.nlm.nih.gov/pubmed/36642841
http://dx.doi.org/10.1002/advs.202205037