Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway

Brain metastases (BRM) are common in advanced lung cancer. However, their treatment is challenging due to the blood‐brain barrier (BBB) and the immunosuppressive tumor microenvironment (ITME). Microparticles (MPs), a type of extracellular vesicle, can serve as biocompatible drug delivery vehicles th...

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Detalles Bibliográficos
Autores principales: Lu, Lisen, Zi, Huaduan, Zhou, Jie, Huang, Jing, Deng, Zihan, Tang, Zijian, Li, Li, Shi, Xiujuan, Lo, Pui‐Chi, Lovell, Jonathan F., Deng, Deqiang, Wan, Chao, Jin, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10015898/
https://www.ncbi.nlm.nih.gov/pubmed/36698296
http://dx.doi.org/10.1002/advs.202206212

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