Cargando…

Genetic risk for schizophrenia is associated with increased proportion of indirect connections in brain networks revealed by a semi-metric analysis: evidence from population sample stratified for polygenic risk

Research studies based on tractography have revealed a prominent reduction of asymmetry in some key white-matter tracts in schizophrenia (SCZ). However, we know little about the influence of common genetic risk factors for SCZ on the efficiency of routing on structural brain networks (SBNs). Here, w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dimitriadis, S I, Perry, G, Lancaster, T M, Tansey, K E, Singh, K D, Holmans, P, Pocklington, A, Davey Smith, G, Zammit, S, Hall, J, O’Donovan, M C, Owen, M J, Jones, D K, Linden, D E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016061/ https://www.ncbi.nlm.nih.gov/pubmed/35830871 http://dx.doi.org/10.1093/cercor/bhac256

Ejemplares similares

Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk
por: Dimitriadis, S. I., et al.
Publicado: (2021)

Structural and Functional Neuroimaging of Polygenic Risk for Schizophrenia: A Recall-by-Genotype–Based Approach
por: Lancaster, Thomas M, et al.
Publicado: (2019)

Morphometric Analysis of Structural MRI Using Schizophrenia Meta-analytic Priors Distinguish Patients from Controls in Two Independent Samples and in a Sample of Individuals With High Polygenic Risk
por: Lancaster, Thomas M, et al.
Publicado: (2021)

Associations between polygenic risk for schizophrenia and brain function during probabilistic learning in healthy individuals
por: Lancaster, Thomas M., et al.
Publicado: (2015)

Risk Factors, Clinical Features, and Polygenic Risk Scores in Schizophrenia and Schizoaffective Disorder Depressive-Type
por: Dennison, Charlotte A, et al.
Publicado: (2021)

Predictive modeling of schizophrenia from genomic data: Comparison of polygenic risk score with kernel support vector machines approach
por: Vivian‐Griffiths, Timothy, et al.
Publicado: (2018)

Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis
por: Pashayan, Nora, et al.
Publicado: (2015)

Exome arrays capture polygenic rare variant contributions to schizophrenia
por: Richards, A. L., et al.
Publicado: (2016)

S139. INVESTIGATING THE GENETIC ARCHITECTURE OF GENERAL AND SPECIFIC PSYCHOPATHOLOGY IN ADOLESCENCE USING SCHIZOPHRENIA POLYGENIC SCORES
por: Jones, Hannah, et al.
Publicado: (2018)

POLARIS: Polygenic LD‐adjusted risk score approach for set‐based analysis of GWAS data
por: Baker, Emily, et al.
Publicado: (2018)

Polygenic impact of common genetic risk loci for Alzheimer’s disease on cerebral blood flow in young individuals
por: Chandler, Hannah L., et al.
Publicado: (2019)

Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer’s disease through polygenic risk and RNA sequencing
por: Crawford, Karen, et al.
Publicado: (2022)

Polygenic dissection of the bipolar phenotype
por: Hamshere, M. L., et al.
Publicado: (2011)

Polygenic risk-stratified screening for cancer: Responsibilization in public health genomics
por: Kerr, Anne, et al.
Publicado: (2019)

Cost-Effectiveness of Risk-Stratified Colorectal Cancer Screening Based on Polygenic Risk: Current Status and Future Potential
por: Naber, Steffie K, et al.
Publicado: (2019)

MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls
por: Cosgrove, D, et al.
Publicado: (2017)

Multimodal Brain Imaging Reveals Structural Differences in Alzheimer’s Disease Polygenic Risk Carriers: A Study in Healthy Young Adults
por: Foley, Sonya F., et al.
Publicado: (2017)

Polygenic risk score for Alzheimer’s disease and trajectories of cardiometabolic risk factors in children
por: Korologou-Linden, Roxanna, et al.
Publicado: (2019)

Polygenic risk scores to stratify cancer screening should predict mortality not incidence
por: Vickers, Andrew J., et al.
Publicado: (2022)

Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse—Brief Report
por: Richardson, Tom G., et al.
Publicado: (2022)

Common alleles contribute to schizophrenia in CNV carriers
por: Tansey, K E, et al.
Publicado: (2016)

Erratum: Common alleles contribute to schizophrenia in CNV carriers
por: Tansey, K E, et al.
Publicado: (2015)

The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
por: Richards, Alexander L, et al.
Publicado: (2020)

Associations Between Schizophrenia Polygenic Liability, Symptom Dimensions, and Cognitive Ability in Schizophrenia
por: Legge, Sophie E., et al.
Publicado: (2021)

Polygenic Risk of Prediabetes, Undiagnosed Diabetes, and Incident Type 2 Diabetes Stratified by Diabetes Risk Factors
por: Liu, Xiaonan, et al.
Publicado: (2023)

Implementation of Risk-Stratified Breast Cancer Prevention With a Polygenic Risk Score Test in Clinical Practice
por: Padrik, Peeter, et al.
Publicado: (2023)

Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC
por: Pashayan, Nora, et al.
Publicado: (2015)

Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia†
por: Hamshere, Marian L., et al.
Publicado: (2013)

Multimodal hippocampal and amygdala subfield volumetry in polygenic risk for Alzheimer's disease
por: Murray, Amy N., et al.
Publicado: (2021)

Polygenic risk for Alzheimer's disease shapes hippocampal scene-selectivity
por: Chandler, Hannah L., et al.
Publicado: (2020)

High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression
por: Hamshere, Marian L., et al.
Publicado: (2013)

Age at onset as stratifier in idiopathic Parkinson’s disease – effect of ageing and polygenic risk score on clinical phenotypes
por: Pavelka, L., et al.
Publicado: (2022)

Stratified proportional win‐fractions regression analysis
por: Wang, Tuo, et al.
Publicado: (2022)

A polygenic resilience score moderates the genetic risk for schizophrenia
por: Hess, Jonathan L., et al.
Publicado: (2019)

Polygenic risk scores for Alzheimer’s disease, and academic achievement, cognitive and behavioural measures in children from the general population
por: Korologou-Linden, Roxanna, et al.
Publicado: (2019)

Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort
por: Grama, Steluta, et al.
Publicado: (2020)

Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog
por: Hingorani, Aroon D, et al.
Publicado: (2023)

Association between genetic risk scoring for schizophrenia and bipolar disorder with regional subcortical volumes
por: Caseras, X, et al.
Publicado: (2015)

Polygenic risk scores: a biased prediction?
por: De La Vega, Francisco M., et al.
Publicado: (2018)

Polygenic risk for schizophrenia, disordered eating behaviours and body mass index in adolescents
por: Solmi, Francesca, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8io9085pe6q1trn589c2i5a11m