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Heterologous SARS-CoV-2 spike protein booster elicits durable and broad antibody responses against the receptor-binding domain

The immunogenicity of mRNA vaccines has not been well studied when compared to different vaccine modalities in the context of additional boosters. Here we show that longitudinal analysis reveals more sustained SARS-CoV-2 spike receptor-binding domain (RBD)-binding IgG titers with the breadth to anti...

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Detalles Bibliográficos
Autores principales: Takano, Tomohiro, Sato, Takashi, Kotaki, Ryutaro, Moriyama, Saya, Fukushi, Shuetsu, Shinoda, Masahiro, Kabasawa, Kiyomi, Shimada, Nagashige, Kousaka, Mio, Adachi, Yu, Onodera, Taishi, Terahara, Kazutaka, Isogawa, Masanori, Matsumura, Takayuki, Shinkai, Masaharu, Takahashi, Yoshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016167/
https://www.ncbi.nlm.nih.gov/pubmed/36922492
http://dx.doi.org/10.1038/s41467-023-37128-1

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