Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway

The decision whether endosomes enter the degradative or recycling pathway in mammalian cells is of fundamental importance for pathogen killing, and its malfunctioning has pathological consequences. We discovered that human p11 is a critical factor for this decision. The HscA protein present on the c...

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Detalles Bibliográficos
Autores principales: Jia, Lei-Jie, Rafiq, Muhammad, Radosa, Lukáš, Hortschansky, Peter, Cunha, Cristina, Cseresnyés, Zoltán, Krüger, Thomas, Schmidt, Franziska, Heinekamp, Thorsten, Straßburger, Maria, Löffler, Bettina, Doenst, Torsten, Lacerda, João F., Campos, António, Figge, Marc Thilo, Carvalho, Agostinho, Kniemeyer, Olaf, Brakhage, Axel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016320/
https://www.ncbi.nlm.nih.gov/pubmed/36893734
http://dx.doi.org/10.1016/j.chom.2023.02.002

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