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Synthesis of functionalised isochromans: epoxides as aldehyde surrogates in hexafluoroisopropanol
The oxa-Pictet–Spengler reaction is arguably the most straightforward and modular way to construct the privileged isochroman motif, but its scope is largely limited to benzaldehyde derivatives and to electron-rich β-phenylethanols that lack substitution along the aliphatic chain. Here we describe a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016621/ https://www.ncbi.nlm.nih.gov/pubmed/36937595 http://dx.doi.org/10.1039/d2sc06692k |