Cargando…

Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018

INTRODUCTION: We assessed progress in HIV viral load (VL) scale up across seven sub-Saharan African (SSA) countries and discussed challenges and strategies for improving VL coverage among patients on anti-retroviral therapy (ART). METHODS: A retrospective review of VL testing was conducted in Côte d...

Descripción completa

Detalles Bibliográficos
Autores principales: Fonjungo, Peter N., Lecher, Shirley, Zeh, Clement, Rottinghaus, Erin, Chun, Helen, Adje-Toure, Christiane, Lloyd, Spencer, Mwangi, Jane W., Mwasekaga, Michael, Eshete, Yohannes Mengistu, Pati, Rituparna, Mots’oane, Tsietso, Mitruka, Kiren, Beukes, Anita, Mwangi, Christina, Bowen, Nancy, Hamunime, Ndapewa, Beard, Rachel S., Kabuje, Anyelwisye, Nabadda, Susan, Auld, Andrew F., Balachandra, Shirish, Zungu, Innocent, Kandulu, James, Alemnji, George, Ehui, Eboi, Alexander, Heather, Ellenberger, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016655/
https://www.ncbi.nlm.nih.gov/pubmed/36920918
http://dx.doi.org/10.1371/journal.pone.0282652
_version_ 1784907448031641600
author Fonjungo, Peter N.
Lecher, Shirley
Zeh, Clement
Rottinghaus, Erin
Chun, Helen
Adje-Toure, Christiane
Lloyd, Spencer
Mwangi, Jane W.
Mwasekaga, Michael
Eshete, Yohannes Mengistu
Pati, Rituparna
Mots’oane, Tsietso
Mitruka, Kiren
Beukes, Anita
Mwangi, Christina
Bowen, Nancy
Hamunime, Ndapewa
Beard, Rachel S.
Kabuje, Anyelwisye
Nabadda, Susan
Auld, Andrew F.
Balachandra, Shirish
Zungu, Innocent
Kandulu, James
Alemnji, George
Ehui, Eboi
Alexander, Heather
Ellenberger, Dennis
author_facet Fonjungo, Peter N.
Lecher, Shirley
Zeh, Clement
Rottinghaus, Erin
Chun, Helen
Adje-Toure, Christiane
Lloyd, Spencer
Mwangi, Jane W.
Mwasekaga, Michael
Eshete, Yohannes Mengistu
Pati, Rituparna
Mots’oane, Tsietso
Mitruka, Kiren
Beukes, Anita
Mwangi, Christina
Bowen, Nancy
Hamunime, Ndapewa
Beard, Rachel S.
Kabuje, Anyelwisye
Nabadda, Susan
Auld, Andrew F.
Balachandra, Shirish
Zungu, Innocent
Kandulu, James
Alemnji, George
Ehui, Eboi
Alexander, Heather
Ellenberger, Dennis
author_sort Fonjungo, Peter N.
collection PubMed
description INTRODUCTION: We assessed progress in HIV viral load (VL) scale up across seven sub-Saharan African (SSA) countries and discussed challenges and strategies for improving VL coverage among patients on anti-retroviral therapy (ART). METHODS: A retrospective review of VL testing was conducted in Côte d’Ivoire, Kenya, Lesotho, Malawi, Namibia, Tanzania, and Uganda from January 2016 through June 2018. Data were collected and included the cumulative number of ART patients, number of patients with ≥ 1 VL test result (within the preceding 12 months), the percent of VL test results indicating viral suppression, and the mean turnaround time for VL testing. RESULTS: Between 2016 and 2018, the proportion of PLHIV on ART in all 7 countries increased (range 5.7%–50.2%). During the same time period, the cumulative number of patients with one or more VL test increased from 22,996 to 917,980. Overall, viral suppression rates exceeded 85% for all countries except for Côte d’Ivoire at 78% by June 2018. Reported turnaround times for VL testing results improved in 5 out of 7 countries by between 5.4 days and 27.5 days. CONCLUSIONS: These data demonstrate that remarkable progress has been made in the scale-up of HIV VL testing in the seven SSA countries.
format Online
Article
Text
id pubmed-10016655
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-100166552023-03-16 Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018 Fonjungo, Peter N. Lecher, Shirley Zeh, Clement Rottinghaus, Erin Chun, Helen Adje-Toure, Christiane Lloyd, Spencer Mwangi, Jane W. Mwasekaga, Michael Eshete, Yohannes Mengistu Pati, Rituparna Mots’oane, Tsietso Mitruka, Kiren Beukes, Anita Mwangi, Christina Bowen, Nancy Hamunime, Ndapewa Beard, Rachel S. Kabuje, Anyelwisye Nabadda, Susan Auld, Andrew F. Balachandra, Shirish Zungu, Innocent Kandulu, James Alemnji, George Ehui, Eboi Alexander, Heather Ellenberger, Dennis PLoS One Research Article INTRODUCTION: We assessed progress in HIV viral load (VL) scale up across seven sub-Saharan African (SSA) countries and discussed challenges and strategies for improving VL coverage among patients on anti-retroviral therapy (ART). METHODS: A retrospective review of VL testing was conducted in Côte d’Ivoire, Kenya, Lesotho, Malawi, Namibia, Tanzania, and Uganda from January 2016 through June 2018. Data were collected and included the cumulative number of ART patients, number of patients with ≥ 1 VL test result (within the preceding 12 months), the percent of VL test results indicating viral suppression, and the mean turnaround time for VL testing. RESULTS: Between 2016 and 2018, the proportion of PLHIV on ART in all 7 countries increased (range 5.7%–50.2%). During the same time period, the cumulative number of patients with one or more VL test increased from 22,996 to 917,980. Overall, viral suppression rates exceeded 85% for all countries except for Côte d’Ivoire at 78% by June 2018. Reported turnaround times for VL testing results improved in 5 out of 7 countries by between 5.4 days and 27.5 days. CONCLUSIONS: These data demonstrate that remarkable progress has been made in the scale-up of HIV VL testing in the seven SSA countries. Public Library of Science 2023-03-15 /pmc/articles/PMC10016655/ /pubmed/36920918 http://dx.doi.org/10.1371/journal.pone.0282652 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Fonjungo, Peter N.
Lecher, Shirley
Zeh, Clement
Rottinghaus, Erin
Chun, Helen
Adje-Toure, Christiane
Lloyd, Spencer
Mwangi, Jane W.
Mwasekaga, Michael
Eshete, Yohannes Mengistu
Pati, Rituparna
Mots’oane, Tsietso
Mitruka, Kiren
Beukes, Anita
Mwangi, Christina
Bowen, Nancy
Hamunime, Ndapewa
Beard, Rachel S.
Kabuje, Anyelwisye
Nabadda, Susan
Auld, Andrew F.
Balachandra, Shirish
Zungu, Innocent
Kandulu, James
Alemnji, George
Ehui, Eboi
Alexander, Heather
Ellenberger, Dennis
Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018
title Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018
title_full Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018
title_fullStr Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018
title_full_unstemmed Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018
title_short Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018
title_sort progress in scale up of hiv viral load testing in select sub-saharan african countries 2016–2018
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016655/
https://www.ncbi.nlm.nih.gov/pubmed/36920918
http://dx.doi.org/10.1371/journal.pone.0282652
work_keys_str_mv AT fonjungopetern progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT lechershirley progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT zehclement progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT rottinghauserin progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT chunhelen progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT adjetourechristiane progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT lloydspencer progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT mwangijanew progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT mwasekagamichael progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT esheteyohannesmengistu progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT patirituparna progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT motsoanetsietso progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT mitrukakiren progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT beukesanita progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT mwangichristina progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT bowennancy progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT hamunimendapewa progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT beardrachels progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT kabujeanyelwisye progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT nabaddasusan progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT auldandrewf progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT balachandrashirish progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT zunguinnocent progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT kandulujames progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT alemnjigeorge progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT ehuieboi progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT alexanderheather progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018
AT ellenbergerdennis progressinscaleupofhivviralloadtestinginselectsubsaharanafricancountries20162018