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Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada

In 2018, the pre-exposure prophylaxis (PrEP) program was initiated in British Columbia (BC), Canada, providing PrEP at no cost to qualifying residents. This observational study discussed the steps to develop key evidence-based monitoring indicators and their calculation using real-time data. The ind...

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Autores principales: Munasinghe, Lalani L., Toy, Junine, Lepik, Katherine J., Moore, David M., Hull, Mark, Bacani, Nic, Sereda, Paul, Barrios, Rolando, Montaner, Julio S. G., Lima, Viviane D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016663/
https://www.ncbi.nlm.nih.gov/pubmed/36920956
http://dx.doi.org/10.1371/journal.pone.0283025
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author Munasinghe, Lalani L.
Toy, Junine
Lepik, Katherine J.
Moore, David M.
Hull, Mark
Bacani, Nic
Sereda, Paul
Barrios, Rolando
Montaner, Julio S. G.
Lima, Viviane D.
author_facet Munasinghe, Lalani L.
Toy, Junine
Lepik, Katherine J.
Moore, David M.
Hull, Mark
Bacani, Nic
Sereda, Paul
Barrios, Rolando
Montaner, Julio S. G.
Lima, Viviane D.
author_sort Munasinghe, Lalani L.
collection PubMed
description In 2018, the pre-exposure prophylaxis (PrEP) program was initiated in British Columbia (BC), Canada, providing PrEP at no cost to qualifying residents. This observational study discussed the steps to develop key evidence-based monitoring indicators and their calculation using real-time data. The indicators were conceptualized, developed, assessed and approved by the Technical Monitoring Committee of representatives from five health authority regions in BC, the BC Ministry of Health, the BC Centre for Disease Control, and the BC Centre for Excellence in HIV/AIDS. Indicator development followed the steps adopted from the United States Centers for Disease Control and Prevention framework for program evaluation in public health. The assessment involved eight selection criteria: data quality, indicator validity, existing scientific evidence, indicator informativeness, indicator computing feasibility, clients’ confidentiality maintenance capacity, indicator accuracy, and administrative considerations. Clients’ data from the provincial-wide PrEP program (January 2018—December 2020) shows the indicators’ calculation. The finalized 14 indicators included gender, age, health authority, new clients enrolled by provider type and by the health authority, new clients dispensed PrEP, clients per provider, key qualifying HIV risk factor(s), client status, PrEP usage type, PrEP quantity dispensed, syphilis and HIV testing and incident cases, and adverse drug reaction events. Cumulative clients’ data (n = 6966; 99% cis-gender males) identified an increased new client enrollment and an unexpected drop during the COVID-19 pandemic. About 80% dispensed PrEP from the Vancouver Coastal health authority. The HIV incidence risk index for men who have sex with men score ≥10 was the most common qualifying risk factor. The framework we developed integrating indicators was applied to monitor our PrEP program, which could help reduce the public health impact of HIV.
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spelling pubmed-100166632023-03-16 Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada Munasinghe, Lalani L. Toy, Junine Lepik, Katherine J. Moore, David M. Hull, Mark Bacani, Nic Sereda, Paul Barrios, Rolando Montaner, Julio S. G. Lima, Viviane D. PLoS One Research Article In 2018, the pre-exposure prophylaxis (PrEP) program was initiated in British Columbia (BC), Canada, providing PrEP at no cost to qualifying residents. This observational study discussed the steps to develop key evidence-based monitoring indicators and their calculation using real-time data. The indicators were conceptualized, developed, assessed and approved by the Technical Monitoring Committee of representatives from five health authority regions in BC, the BC Ministry of Health, the BC Centre for Disease Control, and the BC Centre for Excellence in HIV/AIDS. Indicator development followed the steps adopted from the United States Centers for Disease Control and Prevention framework for program evaluation in public health. The assessment involved eight selection criteria: data quality, indicator validity, existing scientific evidence, indicator informativeness, indicator computing feasibility, clients’ confidentiality maintenance capacity, indicator accuracy, and administrative considerations. Clients’ data from the provincial-wide PrEP program (January 2018—December 2020) shows the indicators’ calculation. The finalized 14 indicators included gender, age, health authority, new clients enrolled by provider type and by the health authority, new clients dispensed PrEP, clients per provider, key qualifying HIV risk factor(s), client status, PrEP usage type, PrEP quantity dispensed, syphilis and HIV testing and incident cases, and adverse drug reaction events. Cumulative clients’ data (n = 6966; 99% cis-gender males) identified an increased new client enrollment and an unexpected drop during the COVID-19 pandemic. About 80% dispensed PrEP from the Vancouver Coastal health authority. The HIV incidence risk index for men who have sex with men score ≥10 was the most common qualifying risk factor. The framework we developed integrating indicators was applied to monitor our PrEP program, which could help reduce the public health impact of HIV. Public Library of Science 2023-03-15 /pmc/articles/PMC10016663/ /pubmed/36920956 http://dx.doi.org/10.1371/journal.pone.0283025 Text en © 2023 Munasinghe et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Munasinghe, Lalani L.
Toy, Junine
Lepik, Katherine J.
Moore, David M.
Hull, Mark
Bacani, Nic
Sereda, Paul
Barrios, Rolando
Montaner, Julio S. G.
Lima, Viviane D.
Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada
title Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada
title_full Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada
title_fullStr Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada
title_full_unstemmed Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada
title_short Process description of developing HIV prevention monitoring indicators for a province-wide pre-exposure prophylaxis (PrEP) program in British Columbia, Canada
title_sort process description of developing hiv prevention monitoring indicators for a province-wide pre-exposure prophylaxis (prep) program in british columbia, canada
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016663/
https://www.ncbi.nlm.nih.gov/pubmed/36920956
http://dx.doi.org/10.1371/journal.pone.0283025
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