HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer

The membrane-associated RING-CH-type finger ubiquitin ligase MARCHF8 is a human homolog of the viral ubiquitin ligases Kaposi’s sarcoma herpesvirus K3 and K5 that promote host immune evasion. Previous studies have shown that MARCHF8 ubiquitinates several immune receptors, such as the major histocomp...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalil, Mohamed I., Yang, Canchai, Vu, Lexi, Chadha, Smriti, Nabors, Harrison, Welbon, Craig, James, Claire D., Morgan, Iain M., Spanos, William C., Pyeon, Dohun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016708/
https://www.ncbi.nlm.nih.gov/pubmed/36867660
http://dx.doi.org/10.1371/journal.ppat.1011171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016708/
https://www.ncbi.nlm.nih.gov/pubmed/36867660
http://dx.doi.org/10.1371/journal.ppat.1011171

Ejemplares similares