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HPV upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer
The membrane-associated RING-CH-type finger ubiquitin ligase MARCHF8 is a human homolog of the viral ubiquitin ligases Kaposi’s sarcoma herpesvirus K3 and K5 that promote host immune evasion. Previous studies have shown that MARCHF8 ubiquitinates several immune receptors, such as the major histocomp...
Autores principales: | Khalil, Mohamed I., Yang, Canchai, Vu, Lexi, Chadha, Smriti, Nabors, Harrison, Welbon, Craig, James, Claire D., Morgan, Iain M., Spanos, William C., Pyeon, Dohun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016708/ https://www.ncbi.nlm.nih.gov/pubmed/36867660 http://dx.doi.org/10.1371/journal.ppat.1011171 |
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