Antiviral activity of amide-appended α-hydroxytropolones against herpes simplex virus-1 and -2

α-Hydroxytropolones (αHTs) have potent antiviral activity against herpes simplex virus-1 and -2 (HSV-1 and HSV-2) in cell culture, including against acyclovir-resistant mutants, and as a result have the potential to be developed as antiviral drugs targeting these viruses. We recently described a con...

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Detalles Bibliográficos
Autores principales: Gazquez Casals, Andreu, Berkowitz, Alex J., Yu, Alice J., Waters, Hope E., Schiavone, Daniel V., Kapkayeva, Diana M., Morrison, Lynda A., Murelli, Ryan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016935/
https://www.ncbi.nlm.nih.gov/pubmed/36936842
http://dx.doi.org/10.1039/d2ra06749h

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