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Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT

The cytoskeletal proteins tubulin and actin are the obligate substrates of TCP-1 ring complex/Chaperonin containing TCP-1 (TRiC/CCT), and their folding involves co-chaperone. Through cryo–electron microscopy analysis, we present a more complete picture of TRiC-assisted tubulin/actin folding along TR...

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Detalles Bibliográficos
Autores principales: Han, Wenyu, Jin, Mingliang, Liu, Caixuan, Zhao, Qiaoyu, Wang, Shutian, Wang, Yifan, Yin, Yue, Peng, Chao, Wang, Yanxing, Cong, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017041/
https://www.ncbi.nlm.nih.gov/pubmed/36921056
http://dx.doi.org/10.1126/sciadv.ade1207