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Structural basis for motilin and erythromycin recognition by motilin receptor

Motilin is an endogenous peptide hormone almost exclusively expressed in the human gastrointestinal (GI) tract. It activates the motilin receptor (MTLR), a class A G protein–coupled receptor (GPCR), and stimulates GI motility. To our knowledge, MTLR is the first GPCR reported to be activated by macr...

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Detalles Bibliográficos
Autores principales:	You, Chongzhao, Zhang, Yumu, Xu, Youwei, Xu, Peiyu, Li, Zhen, Li, Huadong, Huang, Sijie, Chen, Zecai, Li, Jingru, Xu, H. Eric, Jiang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017046/ https://www.ncbi.nlm.nih.gov/pubmed/36921049 http://dx.doi.org/10.1126/sciadv.ade9020

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